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. 2022 Oct 13;14(20):5002. doi: 10.3390/cancers14205002

Table 1.

Baseline Characteristics of Chronic HBV participants stratified by MAFLD.

The Entire Cohort (n = 2032)
Non-MAFLD (n = 1144) MAFLD (n = 888) p-Value
Age 0.355
55.1 (8.8) 54.8 (8.4)
Sex <0.001
 Male 788 (68.9%) 795 (89.5%)
 Female 356 (31.1%) 93 (10.5%)
Hypertension <0.001
 No 768 (67.1%) 448 (50.4%)
 Yes 376 (32.9%) 440 (49.6%)
Diabetes <0.001
 No 900 (78.7%) 572 (64.4%)
 Yes 244 (21.3%) 316 (35.6%)
Dyslipidemia 0.007
 No 871 (76.1%) 629 (70.8%)
 Yes 273 (23.9%) 259 (29.2%)
Liver cirrhosis 0.955
 No 407 (35.6%) 317 (35.7%)
 Yes 737 (64.4%) 571 (64.3%)
Metformin use <0.001
 No 1013 (88.6%) 697 (78.4%)
 Yes 131 (11.4%) 191 (21.5%)
Statin use <0.001
 No 1009 (88.2%) 697 (78.5%)
 Yes 135 (11.8%) 191 (21.5%)
Antiviral therapy 0.292
 No 243 (21.2%) 206 (23.2%)
 Yes 901 (78.8%) 682 (76.8%)
Smoking history <0.001
 Non-smoker 564 (49.3%) 296 (33.3%)
 Ex-smoker 303 (26.5%) 274 (30.9%)
 Current smoker 277 (24.2%) 318 (35.8%)
Alcohol drink <0.001
 None 805 (70.4%) 405 (45.6%)
 Moderate 247 (21.6%) 276 (31.1%)
 Heavy 92 (8.0%) 207 (23.3%)
Physical activity 0.037
 0 to <3 METs-hour/week 344 (30.1%) 297 (33.4%)
 3 to <9 METs-hour/week 272 (23.8%) 202 (22.8%)
 9 to <18 METs-hour/week 330 (28.8%) 273 (30.7%)
 ≥18 METs-hour/week 198 (17.3%) 116 (13.1%)

Abbreviation: MAFLD, metabolic dysfunction-associated fatty liver disease; HBV, hepatitis B virus.