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. 2022 Oct 18;12(10):894. doi: 10.3390/bios12100894

Figure 5.

Figure 5

Examples of optical biosensor approaches for sepsis diagnosis: (a) steps for fabrication of the fiber optic SPR biosensor fort the CRP detection, reprinted with permission of [89] Creative common CC BY 4.0; (b) schematic sandwich assay for PCT detection, reprinted with permission of [90] Copyright 2019 Elsevier B.V.; (c) schematic sensing principle for CRP detection, reprinted from [97] Creative common CC BY 4.0; (d) schematic of the aptamer-gold nanoparticle-based assay for the detection of mouse IL-6, reprinted from [91] Creative common CC BY 4.0; (e) schematic representation of the method for detect urease positive bacteria involved in sepsis, reprinted with permission of [93], Copyright © 2019, American Chemical Society; (f) schematic showing the working principle of selective isolation and detection of bacteria from whole blood involved in sepsis, reprinted [95], Creative common CC BY 4.0.