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Cannabinoid extracts containing either CBD or THC reduce mechanical sensitivity in neuropathic mice. (A) Neuropathic male mice were treated with 6 mg/kg of total cannabinoid at varying ratios of THC:CBD and mechanical sensitivity was measured by von Frey filament. (B) Same as panel A except in female neuropathic mice. n = 10 mice per group. * p < 0.05, ** p < 0.01, **** p < 0.001.
