Table 1.
Patient cohort summary of the 5 selected studies included in this analysis. Variables include sex, mean age, Knosp grade, previous surgery, tumor size, tumor type, complication rate, and remission. Categorical variables are reported as number and percentage. (*) Not all studies described the tumor size. (§) Early remission; one patient didn’t continue the follow-up.
| Patient and Tumor Characteristics | |
|---|---|
| Sex | Number of cases (%) |
| Male | 88 (42.31%) |
| Female | 120 (57.69%) |
| Mean Age | 48.87 |
| Knosp Grade | |
| Grade 0 | 42 (20.19%) |
| Grade 1 | 77 (37.02%) |
| Grade 2 | 53 (25.48%) |
| Grade 3 | 31 (14.90%) |
| Grade 4 | 5 (2.40%) |
| Previous Surgery | 19 (9.13%) |
| Tumor Size * | |
| Macroadenoma | 108 (59.34%) |
| Microadenoma | 74 (40.66%) |
| Tumor Type | |
| Non-functional | 15 (7.21%) |
| ACTH adenoma | 39 (18.75%) |
| Prolactinoma | 25 (12.02%) |
| GH adenoma | 127 (61.065%) |
| TSH-secreting adenoma | 2 (0.96%) |
| Complication Rate | 10/208 (4.81%) |
| Remission § | 196/207 (94.69%) |