Table 1.
Transcript variants of human ROR1 and ROR2 genes. Transcript variants annotated in the GRCh38 dataset from the Genome Reference Consortium were assessed on the Ensembl genome browser (release 104). TSL: transcript support level; TSL1: transcript variants supported by a minimum of one non-suspect mRNA for every splice junction; TSL2: transcript variants supported by multiple ESTs or where the strongest supporting mRNA is flagged as suspect; TSL3: transcript variants supported by a single EST; TSL4: best-supporting EST for the transcript variant is flagged as suspect; TSL5: transcript variants for which the structural model is not supported by a single transcript.
| Transcript Name | Transcript ID | Transcript Length (bp) | Protein Length (aa) | Transcript Classification | Annotation | ||||
|---|---|---|---|---|---|---|---|---|---|
| GENCODE | Ensemble | APPRIS | MANE Select | Transcript Support Level | |||||
| ROR1-v1 | ENST00000371079.6 | 5858 | 937 | Protein coding | basic | Canonical | P1 | MANE Select v0.93 | TSL 1 |
| ROR1-v2 | ENST00000371080.5 | 2305 | 393 | Protein coding | basic | TSL 1 | |||
| ROR1-v3 | ENST00000545203.2 | 5362 | 882 | Protein coding | basic | TSL 5 | |||
| ROR1-v4 | ENST00000482426.1 | 900 | No protein | Processed transcript | TSL 5 | ||||
| ROR2-v1 | ENST00000375708.4 | 4158 | 943 | Protein coding | basic | Canonical | P1 | MANE Select v0.93 | TSL 1 |
| ROR2-v2 | ENST00000375715.5 | 2993 | 704 | Protein coding | basic | TSL 1 | |||
| ROR2-v3 | ENST00000550066.5 | 4360 | No protein | Processed transcript | TSL 2 | ||||
| ROR2-v4 | ENST00000495386.5 | 664 | No protein | Processed transcript | TSL 3 | ||||
| ROR2-v5 | ENST00000546883.1 | 501 | No protein | Processed transcript | TSL 3 | ||||
| ROR2-v6 | ENST00000493846.1 | 370 | No protein | Processed transcript | TSL 3 | ||||
| ROR2-v7 | ENST00000476440.1 | 316 | No protein | Processed transcript | TSL 5 | ||||
| ROR2-v8 | ENST00000548585.2 | 334 | No protein | Retained intron | TSL 5 | ||||