Figure 3.

Effect of GSK3 inhibition on Mcl1 degradation in BCL cell lines. (A) Representative Western blots of Mcl1 over time of 9-ING-41 treatment in the indicated BCL cell lines. (B) Mcl1 and GAPDH were quantified by densitometry and the ratio relative to DMSO treated cells is graphed. Blots in (A) are representative of 3 independent experiments, whose results are all graphed as mean ± SEM in (B). Uncropped blots and densitometry shown in Figure S5.