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. 2022 Oct 14;14(20):5029. doi: 10.3390/cancers14205029

Figure 4.

Figure 4

Differential effect of GSK3 inhibition on IL-6-induced STAT3 activation. (A) Representative Western blot of IL-6-induced pSTAT3Y705 in 9-ING-41 or DMSO-treated mouse BCL cells (A20.2J and Traf3−/− A20.2J). (B) Quantification of 4 replicates including A. (C) Representative Western blot of IL-6-induced pSTAT3Y705 in 9-ING-41 or DMSO-treated primary WT or Traf3−/− mouse B cells. (D) Quantification of 3 replicates including C. Data points are mean ±SEM. *** p < 0.001, * p < 0.05 by repeated-measures ANOVA with Sidak’s multiple comparisons test. Uncropped blots and densitometry shown in Figures S6 and S7.