Table 3.

A comparison between this work and similar works on AD detection based on tau measurement.

Method	Analyte	LOD	Sample	Labeling	Reference
Electrochemical	Tau	0.2 μM	BSA	Label-free	[20]
Electrochemical	Tau	1000 pg/mL, 100,000 pg/mL	PBS, Serum	Label-free	[23]
Electrochemical	Tau	<1 pM	CSF	Label-free	[24]
Electrochemical	Tau-381	0.42 pM	Serum	Labeled	[21]
Photoelectrochemical	Tau-381	0.3 fM	Serum	Labeled	[69]
Electrochemical	full-length 2N4R tau	0.03 pM	Serum	Label-free	[17]
Impedimetric	Tau-441	0.091 pg/mL	Serum, CSF	Labeled	[70]
Electrochemical	P-tau-441	0.02 pM	PBS	Label-free	[71]
Electrochemical	cis pT231-tau	0.02 pM, 0.05 pM	PBS, CSF, Serum	Label-free