Table 5.
Other Cutaneous T-Cell Lymphomas | Gene/Translocation Target |
---|---|
Anaplastic Large cell lymphoma | t(2;5)(p23;q35)-----ALK/NPM (ALK+ systemic) 6p25.3 ----- DUSP22/IRF4 3q28-----TP63 NPM1-TYK2-----JAK/STAT IL6-JAK-STAT mutation DNMT3A, TP53 mutation |
Breast Implant-Associated Anaplastic Large cell lymphoma | 20q13.13 loss |
Primary cutaneous γ/δ T-cell lymphoma | STAT5B mutation-----JAK/STAT SETD2 mutation |
Subcutaneous Panniculitis-like T-cell lymphoma | HAVCR2 mutation-----TIM-3 |
Primary cutaneous aggressive epidermotropic CD8(+) T-cell lymphoma | CAPRIN1-JAK2-----JAK/STAT SELENOI-ABL1 |