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. 2022 Oct 11;14(20):4972. doi: 10.3390/cancers14204972

Table 5.

Summary of genetic abnormalities reported in cutaneous lymphomas other than MF/SS [41,42,43,44,45,46,47].

Other Cutaneous T-Cell Lymphomas Gene/Translocation Target
Anaplastic Large cell lymphoma t(2;5)(p23;q35)-----ALK/NPM (ALK+ systemic)
6p25.3 ----- DUSP22/IRF4
3q28-----TP63
NPM1-TYK2-----JAK/STAT
IL6-JAK-STAT mutation
DNMT3A, TP53 mutation
Breast Implant-Associated Anaplastic Large cell lymphoma 20q13.13 loss
Primary cutaneous γ/δ T-cell lymphoma STAT5B mutation-----JAK/STAT
SETD2 mutation
Subcutaneous Panniculitis-like T-cell lymphoma HAVCR2 mutation-----TIM-3
Primary cutaneous aggressive epidermotropic CD8(+) T-cell lymphoma CAPRIN1-JAK2-----JAK/STAT
SELENOI-ABL1