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. 2022 Oct 5;12(10):1427. doi: 10.3390/biom12101427

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Implantation and noise exposure significantly increase ABR click thresholds. (A) The click hearing thresholds of both groups (left (implanted) (dark grey) and right (not implanted) (light grey)) when included in the study (day −7, naïve, orange) and 7 days after noise (pink) are illustrated. In both groups, a significant threshold increase is observed with a larger before–after difference in the not implanted ears than in the implanted ears. One week after noise, the hearing threshold of the two groups did not differ significantly. (B) The click threshold shifts of left (implanted) and right (not implanted) ears under different conditions. There is no significant difference between the click threshold shift in the left (implanted) ears from day −7 to day 0 pre noise (blue), compared to the threshold shift of the left (implanted) ears from day 0 before noise to day 7 (pink). Right (not implanted) ears show a significant difference in the threshold shift between day 0 pre noise and day 7, when compared to the shift of left (implanted) ears between day −7 and day 0 pre noise and between day 0 pre noise and day 7. ns = not significant; * p ≤ 0.05; *** p ≤ 0.001.