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. 2022 Oct 10;96(20):e01162-22. doi: 10.1128/jvi.01162-22

FIG 4.

FIG 4

Changes in neutralizing sensitivity by L452 spike variants. (A and B) Neutralizing sensitivity expressed as the pseudovirus neutralizing titer (pNT50) of sera from nine donors receiving two and three doses of the vaccines (Table 1) against a panel of lentiviruses pseudotyped with L452 spike mutants in the context of WT D614G (A) and omicron BA.2 (B), respectively. The relative pNT50 (%) values normalized to their parental pairs are shown. The data shown are means ± the SD of triplicate determinations. Statistical significance was determined by Wilcoxon paired signed rank test (*, P < 0.05; **, P < 0.01).