Figure 1.

Decitabine-mediated dose-dependent upregulation of CSPG4 on SKOV-3 ovarian cancer cells. (a) CSPG4-staining of SKOV-3 ovarian cancer cells using a PE-labeled anti-CSPG4 antibody and a corresponding isotype control. One representative donor out of three experiments is depicted. (b) Schematic showing the experimental layout for the decitabine-mediated CSPG4 upregulation. (c,d) CSPG4 staining of SKOV-3 ovarian cancer cells 5 days after addition of decitabine at the indicated concentrations. (c) Data represent geometric means ± SEM of three runs, p values were calculated by Student’s t-test, * indicates p ≤ 0.05. (d) Contour plots of one representative run out of three independent experiments are depicted.