Table 2.

Cyclo- and lipoxygenase inhibition results of the isolated phytosteroids from Fragaria ananassa.

S. No	Conc. (μg/mL)	% COX-2 Inhibition	IC50 μg/mL	% COX-1 Inhibition	IC50 μg/mL	% 5-LOX Inhibition	IC50 μg/mL
Compound 1	1000	83.13 ± 0.80 ***	10.70	66.29 ± 0.43 ***	80.10	87.63 ± 0.64 **	7.40
	500	78.83 ± 0.73 ***		59.56±0.45 ***		82.45 ± 0.55 ***
	250	72.70 ± 0.51 ***		43.54 ± 0.46 ***		76.53 ± 0.41 ***
	125	66.43 ± 0.70 ***		40.57 ± 0.84 ***		71.42 ± 0.46 ***
	62.50	61.06 ± 0.70 ***		22.36 ± 0.49 ***		65.68 ± 0.64 ***
Compound 2	1000	83.17 ± 0.72 ***	8.45	57.57 ±1.18 ***	109.40	85.00 ± 0.30 **	8.71
	500	78.30 ± 0.64 ***		51.67 ± 0.11 ***		78.76 ± 0.58 ***
	250	73.34 ± 0.63 ***		44.86 ± 0.02 ***		73.67 ± 0.61 ***
	125	68.30 ± 0.64 ***		37.72 ± 0.45 ***		67.74 ± 0.61 ***
	62.50	61.93 ± 1.13 ***		32.45 ± 0.65 ***		63.47 ± 0.56 ***
Celecoxib	1000	95.20 ± 0.15	3.22	-	-	-	-
	500	91.17 ± 0.53
	250	86.98 ± 0.85
	125	81.20 ± 0.65
	62.50	77.80 ± 0.37
Montelukast	1000	-	-	-	-	93.55 ± 0.40	4.50
	500					89.37 ± 1.65
	250					85.50 ± 0.40
	125					79.60 ± 0.90
	62.50					74.17 ± 0.72
Aspirin	1000	-	-	75.89 ± 0.20	47.08	-	-
	500			71.88 ± 0.20
	250			66.43 ± 0.29
	125			59.84 ± 0.32
	62.50			51.68 ± 0.22

Data are presented as (mean ± S.E.M); two-way ANOVA followed by Bonferroni test were followed. ** = p < 0.01, *** = p < 0.001.