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. 2022 Oct 15;12(10):1487. doi: 10.3390/biom12101487

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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NNMT promoted the cell proliferation and migration of OSCC cells. (a,d) NNMT mRNA and protein expression in several OSCC cell lines. (b,e) Ectopic expression of NNMT in HN6 cells, confirmed using qPCR and Western blot. (c,f) Knockdown expression of NNMT in OSCC3 cells, confirmed using qPCR and Western blot. (g,h) Ectopic expression of NNMT significantly promoted proliferation and migration ability. (i,j) Knockdown expression of NNMT significantly inhibited proliferation and migration ability. ** and *** represented differences were considered statistically significant with p < 0.01 and p < 0.001, respectively.