Table 2.

Cox-regression analysis of OS and RFS in OSCC patients.

Variables	Univariate Analysis						Multivariate Analysis
	Overall Survival			Recurrence Free Survival			Overall Survival			Recurrence Free Survival
	HR	95%CI	p Value	HR	95%CI	p Value	HR	95%CI	p Value	HR	95%CI	p Value
Gender
Male	1			1
Female	0.578	0.280–1.194	0.139	0.601	0.282–1.282	0.188
Age
<60	1			1
≥60	1.019	0.479–2.167	0.961	0.946	0.452–1.981	0.884
Smoking
No	1			1
Yes	1.412	0.675–2.952	0.359	0.533	0.210–1.456	0.231
T stage
I–II	1			1
III–IV	1.299	0.636–2.652	0.473	0.805	0.378–1.716	0.575
Lymph node metastasis
No	1			1
Yes	3.614	1.661–7.861	0.001 *	1.391	0.684–2.829	0.363	2.198	0.945–5.116	0.068
Chemoradiotherapy
No	1			1
Yes	1.798	0.886–3.647	0.104	1.218	0.600–2.473	0.585
Differentiation
Well	1			1
Moderate/poor	1.196	0.459–3.120	0.714	1.374	0.479–3.940	0.554
DOI
<5 mm	1			1
≥5 mm	4.045	1.653–9.896	0.002 *	2.236	1.039–4.816	0.040 *	1.902	0.692–5.225	0.213	2.087	0.879–4.951	0.095
WPOI
I–III	1			1
IV–V	4.311	1.851–10.040	0.001 *	1.797	0.874–3.693	0.111	1.599	0.595–4.300	0.352
NNMT in TCs
Low	1			1
High	3.234	1.546–6.764	0.002 *	3.051	1.452–6.413	0.003 *	1.960	0.908–4.229	0.086	2.896	1.314–6.379	0.008 *

HR, hazard ratio; CI, confidence interval; * represented differences were considered statistically significant with p < 0.05.