Table 1.
Comparison of changes in time averaged mean velocity (TAMV) in observation and chronic RBC transfusion arms.
| Chronic Transfusion Therapy (n = 5) | Observation Only (n = 5) | p-Value | ||||
|---|---|---|---|---|---|---|
| TAMV in cm/s (SD) | Mean Change in TAMV in cm/s (SD) | TAMV in cm/s (SD) | Mean Change in TAMV in cm/s (SD) | |||
| Pre-randomization | right | 159 (26) | - | 145 (42) | - | 0.14 + |
| left | 183 (65) | - | 134 (68) | - | 0.78 + | |
| Study exit (36 months) | right | 165 (60) | 6 (59) | 137 (47) | −8 (69) | 0.74 ++ |
| left | 168 (67) | −0.15 (101) | 197 (67) | 62 (97) | 0.25 ++ | |
cRBC = chronic blood transfusion, cm/s = centimeters per second, SD = standard deviation. + = compared to observational group pre-randomization, ++ = compared to change in observational group.