Table 4.
Comparison of changes in wall shear stress (WSS) in observation and chronic RBC transfusion arms.
| Chronic Transfusion Therapy (n = 5) | Observation Only (n = 5) | p-Value | ||||
|---|---|---|---|---|---|---|
| WSS Mean in Dyne/cm2 (SD) | Mean Change in WSS (SD) | WSS Mean in Dyne/cm2 (SD) | Mean Change in WSS (SD) | |||
| Pre-randomization | right | 5.64 (1.44) | 36.27 (36.13) | 0.09 + | ||
| left | 6.25 (1.68) | 57.03 (62.6) | 0.11 + | |||
| 36 Month | right | 61.85 (45.82) | 56.20 (44.73) | 41.03 (42.69) | 4.76 (35.02) | 0.08 ++ |
| left | 65.87 (49.26) | 59.62 (49.70) | 70.23 (50.11) | 13.20 (79.69) | 0.30 ++ | |
+ = two tailed p-value for pre-randomization WSS in the observation group vs. the cRBC group. ++ = two tailed p-value for mean change in WSS in the observation group vs. the cRBC group. cRBC = chronic blood transfusion, SD = standard deviation.