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. 2022 Sep 21;12(10):1342. doi: 10.3390/biom12101342

Table 1.

Summary of the physiological effects of ractopamine administration in livestock animals.

Feed Additives Animals Concentration Physiological Effects References
Ractopamine Crossbred gilts
and barrows
0 and 20 ppm Improved feed efficiency, average daily gain (ADG), and decreased cooking loss of loin [27]
Ractopamine Pigs 20 mg/kg Increased ADG, decreased feed conversion ratio (FCR), higher carcass lean proportion [28]
Ractopamine Pigs 0, 5, 10, and 20 mg/kg Increased growth (p < 0.001), better efficiency (p < 0.001), and intensified muscular profile (p < 0.001) [29]
Ractopamine Dogs 1 mg/kg Acute myocardial activity [30]
Ractopamine and clenbuterol Roundworm
(Caenorhabditis elegans)
10 µg/L Decreased brood size, alteration in locomotion behavior, reduced lifespan [31]
Ractopamine Cattle 200 to 350 gm/animal Increased protein deposition and decreased lipogenesis, increased feed efficiency, increased ADG, and increased carcass weight [26]
Ractopamine Cattle 200 mg/animal/day for 28 to 42 days Increased incidence of death (from 0.59 to 1.129/10,000 cattle) [32]
Ractopamine Pigs 0 mg/kg to 7.4 mg/kg Increased ADG (18.8%), improved gain-to-feed efficiency (23.7%), increased carcass yield (0.7% units), and reduced backfat depths (6.3%) as compared to control (0 mg/kg) [33]
Ractopamine + CON basal diet Pigs CON basal diet, CON + 1% ractopamine Increased lean meat in the RAC group, fecal score, and growth performance was nonsignificant [34]