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. 2022 Sep 25;12(10):2309. doi: 10.3390/diagnostics12102309

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Visualization of SA-β-gal in patient tissues. (a) Non-senescent normal colonic crypt mucosa, senescent colon adenoma, and a formally non-senescent colon carcinoma with numerous senescent cells. Reproduced from [27] under the terms of the Creative Commons CC BY license; (b) senescent cancer cells in ovarian tumors from patients who did not receive chemotherapy. Reproduced from [24] under the terms of the Creative Commons CC BY-NC-SA license; (c) prostate cancer tissue, H&E (top), and antibodies to GLB1 (bottom). Reproduced from [33] under the terms of the Creative Commons CC BY license; (d) fluorescence imaging of β-galactosidase in freshly resected human hepatocellular carcinoma. Reproduced from [36] under the terms of the Creative Commons CC BY license.