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. 2022 Oct 14;11(20):3229. doi: 10.3390/cells11203229

Figure 6.

Figure 6

ADSC-EXOs accelerated skin wound healing in diabetic mice via eHSP90. (A) Representative images of skin wounds at days 0, 3, 8, and 13. (B) Quantitative analysis of the wound-closure rates in different treatment groups; * vs. Dia + PBS, # vs. Dia + EXOs + anti-hsp90. (C) H & E staining analysis of wound sections on day 13 post wounding; the double-headed arrows represent edges of the granulation; scale bar: 1 mm. (D) Quantification of the wound edge length shown in (C). (E) Evaluation of collagen deposition by Masson’s trichrome staining in each group; scale bar: 50 μm. (F) Qualification of the stain intensity of blue collagen shown in (E). n = 7. * p < 0.05, ** p < 0.01, **** p < 0.0001, ## p < 0.01.