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. 2022 Oct 14;11(20):3219. doi: 10.3390/cells11203219

Figure 7.

Figure 7

Panx1 channels mediate dye uptake in cholesterol-depleted cell plasma membrane of N2a cells. (A) Representative photomicrographs of mPanx1 transfected and Panx1-null. (C) N2a cells showing EthBr uptake after MβCD and lovastatin with and without 100 µM BzATP treatment. Scale bar: 100 µm. (B,D) Mean ± SEM values of the relative EthBr fluorescence intensity. Values were normalized to those obtained under control conditions. Each point on the graphs represents the mean values of relative EthBr fluorescence changes recorded from all cells present in a field of view obtained from 3–5 independent experiments. p values obtained from ANOVA followed by Dunnett’s test. * p < 0.05, ** p < 0.01, *** p < 0.001.