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. 2022 Oct 21;14(20):5159. doi: 10.3390/cancers14205159

Table 1.

Characteristics of study population and dietary intakes of carotenoids and vitamin A by lung cancer incident status, SCCS.

Characteristic Study Populations p-Value *
Cases Non-Cases
1204 64,346
Age (years) (mean ± SD) 55.1 ± 8.5 51.6 ± 8.5 <0.001
Sex (%) <0.001
Female 49.3 59.6
Male 50.7 40.4
Race (%) 0.07
European American 31.1 28.2
African American 65.8 68.0
others 3.2 3.8
BMI (kg/m2) (%) <0.001
<25 44.8 24.8
25–30 29.6 29.7
≥30 25.7 45.5
Education level (%) <0.001
<High school 40.0 28.4
High school 33.3 33.5
>High school 26.7 38.1
Annual household incomes (%) <0.001
<USD 15,000 67.6 55.3
USD 15,000–USD 49,999 29.1 35.8
≥USD 50,000 3.3 8.9
Smoking status (%) <0.001
Current smokers 75.8 41.1
Former smokers 17.7 21.7
Never smokers 6.5 37.2
Pack years
(the number of packs of cigarettes smoked/day * smoked years) (mean ± SD)
34.1 ± 25.7 22.4 ± 22.0 <0.001
Ever diagnosed with COPD (%) 15.4 8.4 <0.001
Alcohol consumption
(the number of drinks per day), (mean ± SD)
1.7 ± 4.3 1.3 ± 3.6 <0.001
Total energy intake, kcal/day, (mean ± SD) 2699.7 ± 1508.3 2582.0 ± 1458.0 0.006
Vegetable intake, (times/day) <0.001
<1 12.0 11.0
1 43.2 37.4
2 30.6 34.5
≥3 14.2 17.1
Fruit or fruit juice intake, (times/day) <0.001
<1 29.8 23.2
1 32.9 34.9
2 19.7 22.9
≥3 17.7 19.0
Dietary carotenoids intake, median (Q1, Q3) (µg/1000 Kcal)
α-carotene 134.0 (75.9, 249.7) 150.2 (81.4, 281.5) <0.001
β-carotene 1370.8 (859.7, 2355.9) 1504.3 (924.5, 2414.4) 0.009
β-cryptoxanthin 56.2 (31.0, 118.3) 67.9 (35.4, 130.9) <0.001
Lutein and zeaxanthin 1069.9 (670.2, 1869.1) 1137.3 (694.8, 1957.1) 0.04
Lycopene 1856.4 (1280.3, 2791.8) 2012.0 (1353.8, 2866.7) 0.002
Vitamin A, RAE & 353.0 (260.0, 456.7) 353.8 (270.1, 458.7) 0.31

* p-values calculation: age, pack years, alcohol consumption, and total energy intake were calculated by t-test; sex, race, BMI categories, educational level, annual household incomes, smoking status, and ever diagnosed with COPD, vegetables and fruits/fruit juice intake times per day were calculated by chi-square test; carotenoids and vitamin A intake levels were compared by Wilcoxon rank-sum test. & RAE is retinol activity equivalents.