Figure 3.
Normalized enrichment scores (NES) of top 10 most activated and top10 most suppressed pathways comparing High versus Low PSMB9 expression level. Red color indicates activation, while blue color indicates suppression. Reactome gene set from MSigDB curated gene set (C2) was used as input. Pathways related to the immune system and inflammatory response were significantly activated, while pathways related to the extracellular matrix were suppressed.