FIG 2.
CNVs at the ARR3 locus. (A) Span of the 8 different CNVs at the ARR33 locus in C. parapsilosis. The coding sequences are shown by a dark pink box, and the flanking UTRs are shown in a lighter color. The extents of the tandemly repeating units in each of the 8 CNVs are shown by black boxes, labeled CNV-1 to CNV-8 on the left, and their lengths are indicated in white. Exact breakpoints were identified by interrogating split reads from the Illumina data, and the array structure of CNV-2 was verified by MinION sequencing of isolate UCD321. (B) Copy number of ARR3 in each C. parapsilosis isolate. Each dot represents a single isolate: blue isolates from MSK, red from CHU de Nantes (FM), and dark gray from other sources. Medians and interquartile ranges are shown for CNVs present in more than one strain. Dots are jittered for clarity.