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. 2022 Oct 14;14(20):5036. doi: 10.3390/cancers14205036

Table 2.

QUADAS-2 results showing the assessment for the risk of bias and risk of applicability for the studies that were included in the analysis.

Study Risk of Bias Applicability Concerns
Patient Selection Index Test Reference Standard Flow and Timing Patient Selection Index Test Reference Standard
Hoffmann [39] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg
Lopci [38] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Sasikumar [37] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Zhang J [36] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Kumar [35] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Chen [34] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Chandra [33] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Lopci [32] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Li [31] graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg
Lopci [30] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Zhang L [29] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i003.jpg
Wang [28] graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Liu [27] graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Chinnappan [26] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Jiao [25] graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Jain [24] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i002.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg
Emmett [23] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg
Nuo [22] graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i003.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg graphic file with name cancers-14-05036-i001.jpg

Inline graphic Low risk; Inline graphic high risk; Inline graphic unclear risk.