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. 2022 Aug 22;13(5):e02036-22. doi: 10.1128/mbio.02036-22

TABLE 2.

Association of measures of infection with stillbirth and early preterm birtha

Birth outcome groups Clinical chorioamnionitis Histologic chorioamnionitis PCR+ TRC
Stillbirth OR [95% CI] 2.8 [0.7–10.7] 2.0 [0.9–4.2] 7.0 [3.6–13.9] 1.5 [1.3–1.8]
P value 0.12 0.076 <0.001 <0.001
Stillbirth aOR [95% CI] 3.2 [0.7–14.8]b 1.3 [0.5–3.3]c 7.0 [3.3–15.2]b 1.6 [1.3–2.0]b
P value 0.13 0.58 <0.001 <0.001
Early PTB OR [95% CI] 4.7 [1.2–23.0] 10.3 [4.6–23.8] 2.6 [1.3–5.2] 1.3 [1.1–1.5]
P value 0.03 <0.001 0.005 0.002
Early PTB aOR [95% CI] 3.8 [1.0–18.7]d 9.5 [4.2–22.5]d 2.5 [1.2–5.1]e 1.3 [1.1–1.5]d
P value 0.067 <0.001 0.01 0.006
a

OR, odds ratio; CI, confidence interval; aOR, adjusted odds ratio; early PTB, preterm birth <32 weeks of gestation (live birth and stillbirth); TRC, total ASV read counts (log-transformed). P values <0.05 are boldfaced.

b

aOR adjusted for maternal age, race, BMI, parity, multifetal gestation, and gestational age.

c

aOR adjusted for maternal age, race, BMI, parity, and gestational age.

d

aOR adjusted for maternal age and parity.

e

aOR adjusted for maternal age, race, parity, and multifetal gestation.