TABLE 2.
Association of measures of infection with stillbirth and early preterm birtha
| Birth outcome groups | Clinical chorioamnionitis | Histologic chorioamnionitis | PCR+ | TRC |
|---|---|---|---|---|
| Stillbirth OR [95% CI] | 2.8 [0.7–10.7] | 2.0 [0.9–4.2] | 7.0 [3.6–13.9] | 1.5 [1.3–1.8] |
| P value | 0.12 | 0.076 | <0.001 | <0.001 |
| Stillbirth aOR [95% CI] | 3.2 [0.7–14.8]b | 1.3 [0.5–3.3]c | 7.0 [3.3–15.2]b | 1.6 [1.3–2.0]b |
| P value | 0.13 | 0.58 | <0.001 | <0.001 |
| Early PTB OR [95% CI] | 4.7 [1.2–23.0] | 10.3 [4.6–23.8] | 2.6 [1.3–5.2] | 1.3 [1.1–1.5] |
| P value | 0.03 | <0.001 | 0.005 | 0.002 |
| Early PTB aOR [95% CI] | 3.8 [1.0–18.7]d | 9.5 [4.2–22.5]d | 2.5 [1.2–5.1]e | 1.3 [1.1–1.5]d |
| P value | 0.067 | <0.001 | 0.01 | 0.006 |
OR, odds ratio; CI, confidence interval; aOR, adjusted odds ratio; early PTB, preterm birth <32 weeks of gestation (live birth and stillbirth); TRC, total ASV read counts (log-transformed). P values <0.05 are boldfaced.
aOR adjusted for maternal age, race, BMI, parity, multifetal gestation, and gestational age.
aOR adjusted for maternal age, race, BMI, parity, and gestational age.
aOR adjusted for maternal age and parity.
aOR adjusted for maternal age, race, parity, and multifetal gestation.