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. 2022 Sep 30;29(10):7245–7256. doi: 10.3390/curroncol29100571

Table 3.

Summary of all investigated categories and subcategories (17 considered as mandatory, highlighted in bold) in narrative (NR) and standardized structured reports (SSR) of radical prostatectomy specimens according to recommendations by the International Collaboration on Cancer Reporting (ICCR), slightly adapted. The two-sided Fisher’s exact test was performed to compare categories in NR with SSR. p-values < 0.05 were considered statistically significant and are marked with an asterix.

Narrative Reports (NR) Standardized Structured Reports (SSR) p-Values
n = 99 n = 32
Ontario scale level 2 5
CLINICAL DATA
Clinical information 95/99 (96%) 32/32 (100%) 0.5716
Pre-biopsy serum PSA 37/99 (37%) 13/32 (41%) 0.8348
MACROSCOPY
Specimen weight 99/99 (100%) 32/32 (100%) 1
Specimen dimensions 99/99 (100%) 32/32 (100%) 1
Seminal vesicles 99/99 (100%) 32/32 (100%) 1
Lymph nodes 99/99 (100%) 32/32 (100%) 1
→ Laterality 99/99 (100%) 32/32 (100%) 1
Block identification key 99/99 (100%) 32/32 (100%) 1
MICROSCOPY
Histological tumor type 94/99 (95%) 32/32 (100%) 0.3338
How Gleason-Score is being reported 5/99 (5%) 32/32 (100%) <0.0001 *
Gleason-Score
Percentage Gleason pattern 4/5 97/99 (98%) 32/32 (100%) 1
ISUP Grade 77/99 (78%) 31/32 (97%) 0.0144 *
99/99 (100%) 32/32 (100%) 1
Intraglandular extent 94/99 (95%) 32/32 (100%) 0.3338
Extraprostatic extension 67/99 (68%) 32/32 (100%) <0.0001 *
→ Location(s) 25/41 (61%) 11/12 (92%) 0.0765
Extent 10/41 (24%) 12/12 (100%) <0.0001 *
Seminal vesicle invasion 92/99 (93%) 32/32 (100%) 0.1935
Urinary bladder neck invasion 0/99 (0%) 32/32 (100%) <0.0001 *
Intraductal carcinoma of prostate 0/99 (0%) 32/32 (100%) <0.0001 *
Lymphovascular invasion 20/99 (20%) 32/32 (100%) <0.0001 *
Margin status 99/99 (100%) 32/32 (100%) 1
Location of positive margin(s) 29/29 (100%) 4/4 (100%) 1
→ Type of margin positivity
→ Extent of margin positivity 17/29 (59%) 3/4 (75%) 1
→ Gleason pattern of tumor present at positive margin 1/29 (4%) 4/4 (100%) <0.0001 *
Lymph node status 1/29 (4%) 4/4 (100%) <0.0001 *
→ Laterality
→ Maximum dimension of largest deposit 99/99 (100%) 32/32 (100%) 1
7/16 (44%) 2/2 (100%) 0.4706
16/16 (100%) 2/2 (100%) 1
PATHOLOGICAL STAGING
Primary tumor (pT) 99/99 (100%) 32/32 (100%) 1
Regional lymph nodes (pN) 99/99 (100%) 32/32 (100%) 1
Distant metastasis (pM) 0/99 (0%) 11/32 (34%) <0.0001 *