Skip to main content
. 2022 Oct 20;14(20):5148. doi: 10.3390/cancers14205148

Figure 2.

Figure 2

METTL3 expression in PCa cell lines. (A) METTL3 protein expression was examined in the nuclear and cytoplasmic compartments of PCa cell lines LNCaP, LNCaP:C4-2, and 22Rv1. Cytoplasmic and nuclear loading controls used were GAPDH and HDAC1, respectively. Androgen regulation of KLK3 and METTL3 mRNA (B) and METTL3 protein (C) expression was analysed. Veh = vehicle, C = cytoplasmic, N = nuclear. *** p ≤ 0.001, **** p ≤ 0.0001. Molecular weights for proteins are indicated in the full annotated Western blot images (Figures S1–S6).