Table 2.

Eligibility criteria.

Inclusion Criteria	Exclusion Criteria
Clinical study on human fitting with the subject	Narrative review
RCT, prospective or cohort study comparing periodontal indexes of patients treated with multibracket appliance and aligners with follow-up	Retrospective study
RCT, prospective or cohort study comparing periodontal indexes of patients treated with multibracket appliance and aligners without follow-up	Secondary study
	Articles without clinical studies
Articles in English	No full-text available
Studies fitting with the subject using Invisalign technology	No relevant title or abstract
	Patient with antibiotic therapy or periodontitis