Table 2.

Grouping System according to the International Classification of Retinoblastoma.

A	Small	−3 mm in any diameter −located >3 mm from the foveola −located >1.5 mm from the optic disc
B	Large	macular or juxtapapillary location
C	Local Dissemination	discrete vitreous or subretinal seeding
D	Diffuse	−tumor is massive −diffuse vitreous seeding −subretinal seeds
E	Unsalvageable or extensive	−neovascular glaucoma −intraocular or corneal hemorrhage −tumor contact with the lens −tumor in the anterior segment −diffuse infiltrating retinoblastoma
F	Extrascleral	extrascleral spread (optic nerve, orbit or distant metastases)