Table 1.
Baseline characteristics of study population.
| Overall Cohort n = 138 |
|
|---|---|
| Clinical Data | |
| Age (years)–mean ± SD | 82.98 ± 5.05 |
| Gender (male)–% | 52.2 |
| Weight (kg)–mean ± SD | 73.55 ± 12.90 |
| Height (cm)–mean ± SD | 167.44 ± 8.67 |
| BMI (kg/m2)–mean ± SD | 26.21 ± 4.07 |
| BSA (m2)–mean ± SD | 1.82 ± 0.17 |
| NYHA–median ± IQR | 3.00 ± 0.50 |
| STSScore–mean ± SD | 3.01 ± 1.50 |
| Concomitant Disease | |
| Diabetes mellitus–% | 22.5 |
| Arterial Hypertension–% | 81.9 |
| CVD–% | 69.6 |
| CVD–1 vessel–% | 19.6 |
| CVD–2 vessels–% | 13.8 |
| CVD–3 vessels–% | 14.5 |
| Myocardial infarction–% | 3.6 |
| Atrial fibrillation–% | 34.1 |
| Pacemaker–% | 5.1 |
| Malignancy–% | 20.3 |
| Stroke–% | 7.2 |
| PAD–% | 6.5 |
| COPD–% | 8.0 |
| Echocardiography | |
| LVEF (%)–mean ± SD | 53.92 ± 10.32 |
| LVEDD (mm)–mean ± SD | 46.76 ± 6.18 |
| AV Vmax (m/s)–mean ± SD | 4.41 ± 0.52 |
| AV dPmean (mmHg)–mean ± SD | 49.76 ± 11.80 |
| AV dPmax (mmHg)–mean ± SD | 80.71 ± 18.80 |
| sPAP (mmHg)–mean ± SD | 44.94 ± 16.65 |
| sPAP ≥ 40 mmHg–% | 63.0 |
| sPAP ≥ 45 mmHg–% | 50.0 |
| sPAP ≥ 50 mmHg–% | 33.3 |
| TAPSE (mm)–mean ± SD | 22.01 ± 3.72 |
| AVI ≥ II°–% | 16.7 |
| MVI ≥ II°–% | 31.2 |
| TVI ≥ II°–% | 21.7 |
| Computed Tomography | |
| PA ≥ 29 mm–% | 60.9 |
| PA/AA ≥ 0.80–% | 62.9 |
| PA/AA ≥ 0.90–% | 35.7 |
| Laboratory Data | |
| Crea (mg/dL)–median ± IQR | 1.00 ± 0.40 |
| BNP (pg/mL)–median ± IQR | 1797.00 ± 2978.60 |
| cTnI (pg/mL)–median ± IQR | 22.00 ± 30.00 |
| Hkt (%)–median ± IQR | 39.00 ± 7.35 |
| Hb (g/dL)–median ± IQR | 12.90 ± 2.30 |
| CK (U/L)–median ± IQR | 74.00 ± 82.50 |
BMI: body mass index; BSA: body surface area; CVD: cardiovascular disease; PAD: peripheral artery disease; COPD: chronic obstructive pulmonary disease; LVEF: left ventricular ejection fraction; LVEDD: left ventricular end-diastolic diameter; AV Vmax: maximal velocity over aortic valve; AV dpmean: mean pressure gradient over aortic valve; AV dpmax: maximal pressure gradient over aortic valve; sPAP: systolic pulmonary artery pressure; TAPSE: tricuspid annular plane systolic excursion; AVI: aortic valve insufficiency; MVI: mitral valve insufficiency; TVI: tricuspid valve insufficiency; PA: pulmonary artery; AA: ascending aorta; Crea: creatinine; BNP: brain natriuretic peptide; cTnI: cardiac Troponin I; Hkt: hematocrit; Hb: hemoglobin; CK: creatine kinase; SD: standard deviation; IQR: interquartile range.