FIG 3.

Regulatory diversity of Efg1 direct target genes. (A) Venn diagrams summarizing regulation of Efg1 direct target genes in each clinical isolate. Numbers in the Venn diagrams indicate Efg1 direct targets that were significantly differentially expressed between the efg1Δ/Δ mutant and wild type in each background. Note that oppositely regulated genes, i.e., those that were activated by Efg1 in one strain and repressed by Efg1 in another, were counted twice. (B) Graph indicating log₂ fold change for each Efg1 direct target gene displayed in Fig. 1C and D. Data represent means of n = 6 biologically independent samples. Source data are provided in Table S1 in the supplemental material under differential expression.