Figure 1.

Cytoarchitecture of the human fetal spinal cord. (A) Transmission electron microscopy (TEM) images of the central canal of the human fetal spinal cord (scale bar (from left to right) = 20 µm, 10 µm, 2 µm, and 500 nm). The central canal is formed by ependymal cells organized as a pseudostratified epithelium with a large number of cilia in the apical zone (white arrow), nuclei with condensed chromatin (*), and large apical junction complexes (white arrowheads). (B) Representative coronal immunostaining images (complete coronal sections in upper panels and magnified view of the corresponding CC area in the lower panels) of human fetal spinal cords for SOX2 (yellow), Ki67 (yellow), Nestin (green), Gfap (red), NeuN (red), and Olig2 (yellow) (white bar scale= 500 µm; red bar scale = 50 µm).