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. 2022 Oct 11;12(10):2457. doi: 10.3390/diagnostics12102457

Table 3.

Individual proportional hazard models investigating the association between major ad–verse cardiovascular events and late gadolinium enhancement (Location and Pattern).

Adjusted for LVEF, Sex, and Age
n Endpoint HR (95% CI) Individual p Value Overall p Value
Location and pattern
LGE (ring-like) Absent 23 4 (17.4%) 1.00 - 0.004
No ring-like 41 20 (48.8%) 3.59 (0.99–12.39) 0.053
Ring-like 9 5 (55.6%) 6.10 (1.39–26.75) 0.016
LGE (segment) Absent 23 4 (17.4%) 1.00 - 0.001
Single 36 16 (44.4%) 2.96 (0.82–10.69) 0.098
Multiple 14 9 (64.3%) 8.35 (2.10–33.17) 0.003
LGE (Free-wall) No 51 17 (33.3%) 1.00 0.002
Yes 22 12 (54.5%) 2.85 (1.31–6.21) 0.008
LGE (Free-wall) Absent 23 4 (17.4%) 1.00 - 0.001
Septal only 27 12 (44.4%) 2.57 (0.69–9.60) 0.160
Free-wall only 15 7 (46.7%) 4.92 (1.18–20.58) 0.029
Both 8 6 (75%) 10.29 (2.42–43.75) 0.002
LGE (Mid-wall) Absent 23 4 (17.4%) 1.00 -
Without Mid-wall 8 2 (25%) 1.86 (0.30–11.61) 0.507
Mid-wall 42 23 (54.8%) 4.35 (1.23–15.37) 0.023

Values are n or n (%) unless otherwise indicated. p values are quoted for each model overall and for the individual components. LVEF, left ventricular ejection fraction; HR, hazard ratio; CI, confidence interval.