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. 2022 Oct 20;12(10):2543. doi: 10.3390/diagnostics12102543

Table 1.

Features of benign primary cardiac tumor.

Type of Tumor Common Age Common Gender Most Common Site Echo Features CT Features CMR Features
Myxoma Middle age (30–60 y);
younger if associated with Carney complex
Females Left atrium; attached to the fossa ovalis Heterogeneous; narrow pedicle; regular mobile throughout the cardiac cycle Heterogeneous; low-attenuation; calcification seen in 10–20% of patients Smooth, well-defined, lobular or oval; heterogeneous; isointense on T1WI; hyperintense on T2WI; heterogeneous enhancement
Papillary fibroelastoma 40–80 y Men Cardiac valves Small (usually <1.5 cm); round; well-circumscribed; homogeneously textured appearance; a short pedicle; shimmering edges Difficult to observe Difficult to observe
Lipoma No defined age distribution No defined sex distribution Left heart; subendocardial layer Usually hypoechoic in the pericardial space, homogenous and hyperechoic in cardiac chambers; broad base; immobile; well-circumscribed Homogeneous fat attenuation; well-defined; smooth; encapsulated; no contrast enhanced Homogeneous hyperintense on T1WI and complete signal loss in fat suppression sequence; hyperintensity on T2WI; no enhancement
Rhabdomyoma Infants and children No defined sex distribution Usually intramyocardial or intracavitary; no difference in distribution between the left and right heart Multiple; small; round; lobulated; well-circumscribed; homogenous hyperecho Multiple homogeneous low attenuation; no enhancement Isointense on T1WI; hyperintense on T2WI; no enhancement
Fibroma Infants and children No defined sex distribution Ventricles Large; intramural; well-circumscribed; noncontractile; central calcification Homogenous; intramural; soft-tissue attenuation; central calcification; little to no enhancement Iso-intense on T1WI; hypointense on T2WI;
homogenous; no enhancement on resting first-pass perfusion imaging and EGE; hyperenhancement on LGE
Paraganglioma 20–60 y (typically in young adults) No defined sex distribution Left atrium; interatrial septum; aortic body Granular; oval; well-demarcated; broad base; heterogeneous Well-circumscribed; heterogeneous; low attenuation; heterogeneous marked enhancement Isointense or hypointense on T1WI; hyerointense on T2WI; heterogeneous and peripheral rim enhancement
Hemangioma Adulthood Females Ventricles Well-circumscribed; oscillated with the cardiac cycle; blood flow signals on color Doppler flow imaging; obviously enhancement Well-defined; low density or equal density; heterogeneous intense enhancement; “vascular blush” on coronary angiography Heterogeneous isointense or hypointense on T1WI; hyperintense on T2WI; heterogeneous enhancement