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JAV1 and JAV2 are bactericidal. Growth and kill curves of JAV1-treated (A) and JAV2-treated (B) cells are shown. Mid-log-phase S. Typhimurium in M9 + 400 μM EDTA (117 μg/mL) was treated with compound and monitored for absorbance (OD600 [left]) and CFU (normalized to time zero [right]). Means and SEM of three biological replicates are shown. Red dashed lines represent the limits of detection.
