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. 2022 Oct 16;29(10):7816–7831. doi: 10.3390/curroncol29100618

Table 5.

Published details of other double ALK fusion positive NSCLC patients treated with ALK-TKIs.

Ref Year Double Fusion ALK-TKIs Treatment Response
1 Wu, X. et al. [104] 2020 CCNY-ALK ATIC-ALK Crizotinib First line PR > 6 m
2 Wu, X. et al. [105] 2020 NLRC4-ALK;EML4-ALK Crizotinib First line PFS > 10 m
3 Luo, J. et al. [106] 2019 PRKCB-ALK; EML4-ALK Crizotinib
Ceritinib
First line
Second line
PFS: 6 m
PFS > 2 m
4 Qin, B. et al. [107] 2019 BCL11A-ALK; EML4-ALK Crizotinib First line PFS: 13 m
5 Lin, H. et al. [108] 2018 FBXO11-ALK; EML6-ALK Crizotinib Second line PFS > 11 m
6 Yin, J. et al. [109] 2018 DYSF-ALK; ITGAV-ALK Crizotinib Second line PFS > 3 m
7 Tao, H. et al. [110] 2022 ALK-SSH2; EML4-ALK Crizotinib First line PFS: 9 m
8 Tao, H. et al. [110] 2022 ARID2-ALK; EML4-ALK Crizotinib First line PFS: 12 m
9 Guo, J. et al. [111] 2020 CDK15-ALK; EML4-ALK Crizotinib Second line PFS: 23 m
10 Zeng, H. et al. [68] 2021 PDK1-ALK; STRN-ALK Alectinib First line PFS > 11 m
11 Zhai, X. et al. [112] 2022 ALK-GCA; EML4-ALK Alectinib First line PFS > 20 m