FIG 5.

Associations between predicted functional pathways and CF microbes. The y axis contains the 30 most prevalent microbial taxa, and the x axis contains a curated subset of predicted functional pathways, including fermentation, the electron transport chain, respiration, and metabolism pathways. Significance annotations indicate microbes/pathways that are significantly impacted by hyperoxia after Bonferroni-Hochberg multiple-hypothesis correction with a threshold q value of <0.1; blue boxes indicate q values of <0.1, gray boxes indicate q values of ≥0.1 The main heat map plots the Spearman rank correlation of each microbe against each of the selected pathways. Dendrograms relate microbes by functional pattern and functions by microbial pattern.