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Flow chart of patient selection. Abbreviations: ICI-plus: anti-PD1/PD-L1 plus other therapy; chemo-targeted: chemotherapy with or without targeted therapy; BSC: best supportive care; CTLA-4 = cytotoxic T lymphocyte-associated antigen-4; dMMR = mismatch repair-deficient; MSI = microsatellite instability; PD1 = programmed death 1; PD-L1 = programmed death ligand-1; RFA = radiofrequency ablation; TACE = transcatheter arterial chemoembolization.
