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. 2022 Oct 12;13:916098. doi: 10.3389/fimmu.2022.916098

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Copyright © 2022 He, Zhou, Ji, Zhang, Lv, Quan, Zhang, Zhao, Cui, Li, Liu, Zhang, Shen, Fang, Yang, Zhang, Cui, Zhang and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Animal modeling process. After 1 week of adaptive feeding, 51 female C56BL/6J mice were randomly divided into the normal control (NC) (n = 6), solvent control (SC) (n = 5), and experimental autoimmune myasthenia gravis (EAMG) (n = 40) groups. The mice in the SC group and the EAMG group received the first immunization in the first week, the second immunization in the fifth week, the third immunization in the ninth week, and the fourth immunization in the eleventh week. The EAMG model was assessed in the twelfth week.