Table 1.
Baseline characteristics of SAPH and SA patients. FVC % predicted: forced vital capacity % of predicted value; DLCO SB % predicted: single-breath diffusing capacity of the lung for carbon monoxide % predicted; Mean PAP: mean pulmonary arterial pressure; PVR: pulmonary vascular resistance; PCWP: pulmonary capillary wedge pressure; ND: parameter was not determined.
| SAPH (n = 39) | SA (n = 39) | p-Value | ||
|---|---|---|---|---|
| Male, n (%) | 19 (48.7) | 19 (48.7) | 1.00 | |
| Age mean (SD), y | 59.2 (11.3) | 60.9 (10.9) | 0.50 | |
| Ancestry | White, n (%) | 27 (69.2) | 27 (69.2) | 1.00 |
| Black, n (%) | 9 (23.1) | 9 (23.1) | ||
| Hindustan, n (%) | 3 (7.7) | 3 (7.7) | ||
| Scadding stage (n = 38; n = 39) |
0, n (%) | 2 (5.3) | 8 (20.5) | 0.016 |
| 1, n (%) | 4 (10.5) | 3 (7.7) | ||
| 2, n (%) | 4 (10.5) | 9 (23.1) | ||
| 3, n (%) | 2 (5.3) | 6 (15.4) | ||
| 4, n (%) | 26 (68.4) | 13 (33.3) | ||
| Lung fibrosis score (n = 38; n = 39) |
<5%, n (%) | 9 (23.7) | 22 (56.4) | <0.001 |
| 5–20%, n (%) | 1 (2.6) | 7 (17.9) | ||
| >20%, n (%) | 28 (73.7) | 10 (25.6) | ||
| FVC % predicted, mean (SD) (n = 37; n = 36) | 66.6 (19.4) | 94.2 (23.1) | <0.001 | |
| DLCO SB% predicted, mean, mean (SD) (n = 32; n = 32) |
47.8 (18.5) | 68.4 (15.2) | <0.001 | |
| Mean PAP mmHg, mean (SD) | 37.4 (10.9) | ND | ||
| PVR Wood units, mean (SD) (n = 36; ND) | 5.6 (3.1) | ND | ||
| Cardiac output L·min-1, mean (SD) (n = 38; ND) | 5.7 (1.8) | ND | ||
| PCWP mmHg, mean (SD) (n = 37; ND) | 9.7 (3.6) | ND |