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. 2022 Oct 18;11(20):3245. doi: 10.3390/foods11203245

Table 3.

Saffron by-products of different geographical origins, major components, and applications.

By-Product (Origin and Type of Extract) Major Components Concentration Application Ref.
Sepals (Fiesole, Italy; ethanolic) Trans-4-GG
Trans-3-Gg
Cis-2-G
Kaempferol-3-sophoroside
Quercetin diglucoside
Kaempferol glucoside
Kaempferol sinapoyl glucoside
3.1
0.8
0.2
6.4
0.4
0.4
0.3
mg/g Phytochemicals [98]
Stamens (Fiesole, Italy; ethanolic) Trans-4-GG
Trans-3-Gg
Cis-4-GG
Trans-2-G
Kaempferol-3-sophoroside
Quercetin diglucoside
Methyl quercetin derivative
Methyl quercetin diglucoside
Kaempferol-3-sophoroside-7-glucoside
112.2
33.4
22.0
20.7
1.7
1.0
0.7
0.6
0.5
mg/g Phytochemicals [98]
Sepals (Perugia, Italy; ethanolic) Traces of crocin
Kaempferol-3-sophoroside
Quercetin diglucoside
Kaempferol glucoside
Kaempferol sinapoyl glucoside
nd
8.3
0.7
0.4
0.3
mg/g Phytochemicals [98]
Stamens. (Perugia, Italy; ethanolic) Trans-4-GG 4 mg/g Phytochemicals [98]
Trans-2-G 1.3
Methyl quercetin diglucoside 2.1
Quercetin diglucoside 1.2
Methyl quercetin derivative 1.2
Kaempferol-3-sophoroside-7-glucoside 0.9
Kaempferol diglucoside 0.8
Petals (Srinagar, Jammu & Kashmir, India; aqueous) Not detected Kashmir dye green and yellow tones [66]
Petals (Kerman, Iran; aqueous) Methanol 355 ppb Volatile compounds in the pharmaceutical industry [42]
Biogenix aldehyde fragment 303
Acetic acid 492
Isobutanal 694
Furanone 6397
2,3-butanedione 524
Petals (Sardinia, Italy; aqueous) Kaempferol-3-O-sophoroside 2790 mg/L Antioxidant and colon anticancer activities. [147]
Phenylalanine 1072
Delphinidin 3,5-di-O-glucose 822
Tyrosine 619
Kaempferol-3,7-di-O-glucoside 368
Isorhamnetin-3-O-rutinoside 268
Quercetin 3-O-sophoroside 207
Petals (Northeast, Iran; ethanolic and aqueous) Pelargonidin 3,5-glycosides 56.1 % Antioxidant and colorant activities. [148]
3,5 cyanidin-diglycosides 20.9
Petunidin 15.5
Delphinidin 3-glycosides 4.1
Pelargonidin 3-glycosides 3.4
Petals and anthers (Navelli, Italy; ethanolic, oil, and aqueous) Crocin 0.6 % Antioxidant and anti-inflammatory (in vivo; in vitro). [149]
Catechin 0.2
Rutin 0.1
Epicatechin 0.08
p-OH benzoic acid 0.04
Safranal 0.02
Vanillic acid 0.02
Galic acid 0.09
Safranal 0.05
Quercetin 0.01
Petals (Torbat Heydariyeh region, Iran; ohmic extraction) Crocin 81.2 % Source of natural flavoring, coloring, and antioxidants. [41]
Safranal 5.5
Catechin 1.4
Epicatechin 1.2
Delphinidin 3,5-di-O-glucose 74.2
Petunidin 3-O-glucoside 10.3
Petunidin 2,5-di-O-glucoside 8.6
Quercetin 3-O-glucoside 59.5
Kaempferol-3-O-sophoroside 8.2
Kaempferol-3-O-glucoside 6.1
Quercetin 3-O-sophoroside 5.5
Kaempferol 5.4
Petals. (Torbat Heydariyeh region, Iran; ultrasound extraction) Crocin 79.02 % Source of natural flavoring, coloring, and antioxidants. [41]
Safranal 4.03
Delphinidin 3,5-di-O-glucose 67.88
Petunidin 3-O-glucoside 10.74
Petunidin 3,5-di-O-glucoside 7.39
Quercetin 3-O-glucoside 54.32
Kaempferol-3-O-sophoroside 8.16
Kaempferol-3-O-glucoside 5.27
Quercetin 3-O-sophoroside 5.12
Petals. (Torbat Heydariyeh region, Iran; microwave extraction) Crocin 77.42 % Source of natural flavoring, coloring, and antioxidants. [41]
Safranal 5.03
Epicatechin 1.02
Vanillic acid 1.03
Delphinidin 3,5-di-O-glucose 56.36
Petunidin 3-O-glucoside 11.44
Malvidin O-glucoside 7.94
Quercetin 3-O-glucoside 59.49
Kaempferol-3-O-sophoroside 8.16
Kaempferol-3-O-glucoside 6.13
Quercetin 3-O-sophoroside 5.51
Kaempferol 5.42