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Mechanism of action of diclofenac potassium. NF-κb: Nuclear Factor-Kappa B; COX-2: Cyclooxygenase-2; PGE2: Prostaglandin E2 (dinoprostone); IL-1β: Interleukin-1beta (lymphocyte activating factor (LAF)); IL-6: Interleukin-6 (B-cell stimulatory factor -2 (BSF-2)); IL-8: Interleukin-8 (α chimiokine); TNF-α: Tumor Necrosis Factor-alpha; VEGF: Vascular Endothelial Growth Factor.
