Table 1.
Visit | 0 | 1 | 2 | 3 | 4 | 5 | 6 | UV * |
---|---|---|---|---|---|---|---|---|
Week | −7 | 1 | 5 | 9 | 13 | 25 | 37 | - |
Visit Window | - | 2 | ±7 | ±7 | ±7 | ±7 | ±7 | - |
Informed consent for the study | ● | |||||||
Demographic information | ● | |||||||
Participation in other clinical trials | ● | |||||||
Medical history | ● | |||||||
Confirmation of diagnosis of COVID-19 infection | ● | |||||||
Medication history | ● | |||||||
Vital signs | ● | ● | ● | ● | ● | ● | ● | ● |
Electrocardiogram | ● | ● | ● | |||||
Laboratory test | ● | ● | ● | |||||
Blood collection for immune response and metabolite analysis | ● | ● | ● | ● | ● | |||
Pregnancy ** | ● | |||||||
Evaluation of fatigue or brain fog | ● | |||||||
CIS | ● | ● | ● | ● | ● | ● | ● | |
VAS (0–100) score for fatigue or brain fog | ● | ● | ● | ● | ● | ● | ● | |
Inclusion/exclusion criteria | ● | |||||||
KM syndrome differentiation | ● | |||||||
Prescription of herbal medicine *** | ● | ○ | ○ | |||||
Drug adherence | ● | ● | ● | ● | ||||
Check for combination therapy | ● | ● | ● | ● | ● | ● | ||
ChFQ | ● | ● | ● | ● | ● | ● | ● | |
EQ-5D-5L | ● | ● | ● | ● | ● | ● | ● | |
PSQI-K | ● | ● | ● | ● | ● | ● | ● | |
K-MoCA | ● | ● | ● | ● | ● | ● | ● | |
CFQ | ● | ● | ● | |||||
BDI | ● | ● | ● | ● | ● | ● | ● | |
Digit span test in K-WAIS (DF, DB, and DF-DB) | ● | ● | ● | ● | ||||
K-BNT-15 | ● | ● | ● | ● | ||||
Adverse events check | ● | ● | ● | ● | ● | ● | ● |
●, check on visit; ○, if applicable * UV, unscheduled visit (), ** only fertile women, *** Evaluation for the continuation of herbal medicine administration at 5th and 9th weeks.