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. 2022 Sep 26;14(9):e29609. doi: 10.7759/cureus.29609

Table 2. Benzodiazepine vs non-benzodiazepine users.

MME: Milligram morphine equivalents

Variable Non-Benzodiazepine User N=530 Benzodiazepine User N=104 p value
Age (SD) 59.6 (14.8) 58.5 (14.2) 0.494
Gender     0.261
Female 371 (70.0%) 67 (64.4%)  
Male 159 (30.0%) 37 (35.6%)  
Initial Postoperative Opioid Prescription Factors      
        Total MME/Prescription (SD) 138.3 (123.7) 142.7 (190.7) 0.762
        Duration in days (SD) 4.2 (3.8) 4.3 (4.8) 0.863
        Quantity of Pills (SD) 21.6 (13.6) 21.3 (17.8) 0.821
Preoperative Opioid Use     0.014
No 389 (73.4%) 64 (61.5%)  
Yes 141 (26.6%) 40 (38.5%)  
1+ Opioid Refill     0.003
No 383 (72.3%) 60 (57.7%)  
Yes 147 (27.7%) 44 (42.3%)  
# of Postoperative Opioid Refills 2.3 (2.2) 3.6 (3.9) 0.009
Prolonged 3-6 Month Opioid Use     0.004
No 465 (87.7%) 80 (76.9%)  
Yes 65 (12.3%) 24 (23.1%)