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. 2022 Sep 26;14(9):e29609. doi: 10.7759/cureus.29609

Table 3. Preoperative opioid users only vs preoperative opioid users with concurrent benzodiazepine use.

MME: Milligram morphine equivalents

Variable Preoperative Opioid User Only (N=141) Preoperative Opioid Use with Concurrent Benzodiazepine Use (N=40) p value
Age (SD) 57.9 (15.2) 59.1 (13.4) 0.652
Gender     0.555
Female 99 (70.2%) 30 (75.0%)  
Male 42 (29.8%) 10 (25.0%)  
Initial Postoperative Opioid Prescription Factors      
        Total MME/Prescription (SD) 197.0 (198.0) 196.7(284.5) 0.996
        Duration in days (SD) 5.5 (6.1) 5.6 (7.2) 0.915
        Quantity of Pills (SD) 27.5 (20.5) 26.8 (24.9) 0.862
1+ Opioid Refill     0.051
No 74 (52.5%) 14 (35.0%)  
Yes 67 (47.5%) 26 (65.0%)  
# of Postoperative Opioid Refills 3.4 (2.8) 5.1 (4.4) 0.032
Prolonged 3-6 Month Opioid Use     0.058
No 100 (70.9%) 22 (55.0%)  
Yes 41 (29.1%) 18 (45.0%)