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Cumulative release profiles for PTX loaded in G4-EG(NaOH)0.75 hydrogel. N,N-Diethylnicotinamide (1.5 M in PBS, pH 7.4) solution was used as the release medium to maintain an infinite sink condition. Samples were taken at predetermined time intervals and assayed for PTX by isocratic reverse-phase HPLC (mean ± S.E.M., n = 3).
