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. 2022 Oct 11;13(10):1837. doi: 10.3390/genes13101837

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Functional enrichment analysis performed on the DEGs identified between the two risk subgroups in TCGA cohort. (A) Volcano plot displaying DEGs between the two risk subgroups by the threshold of |log2FC| ≥ 0.4 and adjusted p-value < 0.01. Specific DEGs involved in the selected pathways are displayed. (B) KEGG pathways significantly enriched in the high-risk group in the bubble plot form. (C,E,F) Selected canonical biological process associated GSEA pathways in the high-risk group. (D) Representative GO terms enriched in terms of biological process (BP), cellular component (CC) and molecular function (MF) respectively in the high-risk group. p value is showed as: * p < 0.05.