TABLE 3.

Correlation coefficients between viral neutralization and immunogenicity levels in subgroups based on vaccine dosing interval (VDI) and between-cohort comparisons

Immunogenicity measurea	Correlation coefficient (95% CI) short VDI	Correlation coefficient (95% CI) long VDI	Fisher’s Z	P value
Anti-spike total	0.50 (0.28 to 0.67)	0.70 (0.54 to 0.82)	−1.70	0.090
Anti-spike IgG	0.37 (0.12 to 0.58)	0.63 (0.45 to 0.77)	−1.88	0.060
Anti-RBD IgG	0.38 (0.14 to 0.59)	0.50 (0.28 to 0.67)	−0.80	0.43
Anti-NTD IgG	0.34 (0.088 to 0.55)	0.55 (0.34 to 0.71)	−1.41	0.16
ACE-2 RBD	0.39 (0.15 to 0.59)	0.73 (0.58 to 0.83)	−2.76	0.0058

^aAll measured as concentrations.