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. 2022 Oct 14;19(20):13280. doi: 10.3390/ijerph192013280

Table 1.

Summary of studies investigating new-onset diabetes mellitus after COVID-19 recovery.

Reference Country Study Type Sample Size Follow-Up Timeframe Results
Montefusco, L. et al. [9] Italy Retrospective observational cohort study 551 Six months Among 151 patients who exhibited new-onset hyperglycaemia at hospital admission for COVID-19, persistent hyperglycaemia continued to be observed in 52 (35%) patients, overt diabetes was diagnosed in about 2% of patients and the remaining 63% of patients showed remission and became normoglycemic.
Chen, M.et al. [10] China Prospective study 64 Three and six months Fasting C-peptide [mmol/L] Mean ± SD
  • Baseline 0.35 ± 0.24;

  • 3-month follow-up 2.36 ± 0.98;

  • 6-month follow-up 2.52 ± 1.11;

  • p-value < 0.001.

Fasting blood glucose [mmol/L] Mean ± SD
  • Baseline 5.84 ± 1.21;

  • 3-month follow-up 4.95 ± 0.76;

  • 6-month follow-up 5.40 ± 0.68;

  • p-value < 0.003.

Nesan, G. et al. [11] India Longitudinal study 354 Three months Ten newly diagnosed with diabetes mellitus: six (66.6%) females and three (33.3%) males; p = 0.002.
Ayoubkhani, D. et al. [12] England Retrospective cohort study 47,780 Five months Rate of new-onset diabetes was raised in post-COVID patients with 29 diagnoses per 1000 patient-years.
Huang, C. et al. [13] China Ambidirectional cohort study 1733 Six months Fifty-eight patients without a self-reported history of diabetes were newly diagnosed with the condition at follow-up.

COVID-19, coronavirus disease 2019; mmol/L, millimoles per litre; p, p-value; SD, Standard Deviation.